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10Panx

10Panx is a mimetic inhibitory peptide of panx1, which blocks pannexin-1 gap junctions, inhibits p2x7-mediated dye uptake, atp-mediated il-1β release and caspase-1 activation, but does not alter membrane current in macrophages in vitro.

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CAT#	R0961
CAS	955091-53-9
M.F/Formula	C58H79N15O16
M.W/Mr.	1242.37
Sequence	Trp-Arg-Gln-Ala-Ala-Phe-Val-Asp-Ser-Tyr
Labeling Target	Gap Channels
Purity	>98%
Activity	Inhibitor

CAT#	Product Name	Inquiry
R1409	HAEGTFTSDVS	Inquiry
R1200	Angiotensin II (1-4), human	Inquiry
R1391	Glycoprotein 276-286	Inquiry
PI-008	BIM-23190	Inquiry
R1419	H-Gly-Gly-Pro-OH	Inquiry

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The effect of thymopentin in the treatment of chronic severe viral hepatitis B

The thymopentin is a small peptide consisting of 5 amino acid residues (Arg-Lys-Asp-Val-Tyr) from thymosin. It h ...

Function of KYL Solution on the Cold Preservation of Liver

Appropriate perfusion preservation solution is of great significance for reducing or slowing down various damage ...

Function of carnosine in skin, food and body

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The Function of Darifenacin Hydrobromide in over Active Bladder

Studies on the binding affinities of darifenacin hydrobromide and human muscarinic receptor subtypes show strong ...

Function of 10Panx in the pathogenesis of epilepsy

10Panx is a panx 1 mimetic inhibitor that easily and reversibly inhibits panx1 currents. In cells that are diffi ...

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Storage	-20°C
InChI	InChI=1S/C58H79N15O16/c1-29(2)47(56(87)70-42(26-46(77)78)53(84)72-44(28-74)55(86)71-43(57(88)89)24-33-16-18-35(75)19-17-33)73-54(85)41(23-32-11-6-5-7-12-32)69-49(80)31(4)65-48(79)30(3)66-51(82)40(20-21-45(60)76)68-52(83)39(15-10-22-63-58(61)62)67-50(81)37(59)25-34-27-64-38-14-9-8-13-36(34)38/h5-9,11-14,16-19,27,29-31,37,39-44,47,64,74-75H,10,15,20-26,28,59H2,1-4H3,(H2,60,76)(H,65,79)(H,66,82)(H,67,81)(H,68,83)(H,69,80)(H,70,87)(H,71,86)(H,72,84)(H,73,85)(H,77,78)(H,88,89)(H4,61,62,63)/t30-,31-,37-,39-,40-,41-,42-,43-,44-,47-/m0/s1
InChI Key	JCJASTVQGSKHKZ-QZHJRRRASA-N
Isomeric SMILES	C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)N
BoilingPoint	N/A
Melting Point	N/A