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For the last few decades scientist have been researching the involvement of the immune system in cancer development to discover a potential cure. Immune cells have been known to play an important role in regulating tumor progression, thus stimulating immune reactions towards tumors can be an attractive therapeutic targeting cancer. More and more clinical data has been shown positive signs of immunotherapy as a potential cure for cancer.
Immunotherapy using checkpoint inhibitors (especially PD-1/PD-L1 inhibitors) has evolved into the most promising therapy for cancer patients. However, most of these inhibitors are surrogate antibodies, and their large size may limit their tumor permeability, resulting in sub-optimal efficacy.
Creative Peptides provides customized checkpoint peptide inhibitors synthesis service for immunotherapy companies and academic institutions to promote effective cancer therapy methods development.
As a class of tumor-specific antigens, neoantigens are expressed only by tumor cells, while normal cells do not. Therefore, for the neoantigen vaccine, it is conceivable that the immune response can precisely target the patient's tumor cells while protecting their healthy cells from immune attacks, which can prevent side effects.
At Creative Peptides, we provide a one-stop service for the development of new antigen peptide vaccines, from target site recognition to the synthesis of highly immunogenic peptide antigens.
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
What are copper peptides? Copper peptides are tripeptide molecules composed of three amino acids that combine with copper io ...
In 1979, GOLDSTEIN et al. extracted an opioid-active 17 peptide from the pituitary of pigs and named it dynorphi ...
Muramyl dipeptide (MDP) is the smallest structural unit with immune activity in the skeleton of bacille calmette ...
Topotecan (TPT) is a water-soluble, semi-synthetic camptothecin derivative developed by Smithkline Beecham, USA. ...
The peptide st-Ht31 P, A-kinase anchoring protein (AKAP) inhibitor, has the negative control for st-Ht31. In DRG ...