Peptide Characterization
* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
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Peptide is a product of protein hydrolysis. After being degraded by enzymes, the protein ingested by the human body is mainly digested and absorbed in the form of peptides. The peptide in the body can regulate the physiological functions of all cells and can provide nutrients to the body. The composition is basically the same, and the peptide has a more stable processing property and a more absorbing victory property than the protein, which will greatly broaden the application range of the protein.
The relationship between structure and function of peptides is well reflected in the development of peptide drugs. The complete determination of the structure of the peptide itself helps us to carry out the next study of the peptide, so that the target peptide can reach our ideal physical and chemical properties and apply it to more fields.
Creative Peptides is equipped with advanced analytical instruments, combined with the research attitude of laboratory research experts, so that we can provide customers with a very comprehensive peptide analysis service. Accurate results can accelerate your research progress.
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Analytical method development helps to establish the stability of product-specific acceptance criteria and results, while verification analysis methods prove that the analysis program is suitable for its purpose. Creative Peptides has vast experience in analytical and bioanalytical analysis method development and validation for a variety of platforms including HPLC, LC/MS/MS, GC/MS or GC/FID, ICP/MS, and ligand binding assays.
Chemists use chemical synthesis techniques to introduce new chemical groups into a peptide, or to transform its structure to better perform its physiological activities. The ability to draw conclusions about a compound depends on the structural features that can be characterized. Creative Peptides can provide customers with a full range of peptide characterization services in a variety of effective ways to fully understand the structure of peptides and accelerate scientific research.
This technique is mainly used for peptide mass analysis. We obtained the theoretical peptide mass by computer program and compared it with the quality of our experimental peptides, and statistically analyzed the results to find the best match. Creative Peptides provides Peptide Mass Fingerprinting (PMF) analysis and ions searching against database for rapid identification of proteins.
There is a relationship between structure and activity that is the Structure Activity Relationship (SAR). We can usually predict the biological effects through peptide structures, using known molecular structure data to compare with new peptides, because similar structures may have similar physical and physiological properties. Creative Peptides will provide our customers with a complete SAR report after completing the SAR analysis, including decipher SAR, detailed pharmacophores, key activity changes highted, SAR data interpretation, etc.
Reference
- Goodman, M., Felix, A., Moroder, L., & Toniolo, C. (2004). Houben-Weyl Methods of Organic Chemistry Vol. E 22c, Supplement: Synthesis of Peptides and Peptidomimetics. Georg Thieme Verlag.
