Large Scale Peptide Synthesis

How to produce peptide in a large scale

Peptides are widely used in the fields of functional detection, antibody preparation, and especially drug discovery. Nowadays, it is more practical to obtain more peptides (>1g) at a time for the production of biological additives, health care or therapeutic products which contain peptides.

At present, commonly used peptide synthesis methods are solution-phase methods, solid-phase methods and hybrid approaches. Solid-phase method is currently the mainstream method for the preparation of peptides, which can be used to prepare any desired active peptides. It is very suitable for the synthesis of high nutritional value, medium length pharmaceutical peptides. With the increase in the number of products, solution-phase methods may be more favorable.

Available Services

Creative Peptides have many years of experience in peptide synthesis, and our chemical synthesis team will build production solutions based on customer needs. Our expertise in the custom synthesis of peptides allows us to produce large-scale, high-quality peptides, which with high success rates and good purity, covering a wide range of peptides in research, production, etc. Cost analysis, project review, process optimization and quality control reports are delivered to our customers in a timely manner to ensure that you get the most satisfactory peptide products.

Service Features:

• Development and optimization of production processes
• Efficient production
• Flexible tailor-made solutions
• One-to-one project management

The methods of obtaining peptides and protein molecules have an enormous growth over the past few decades. Based on biological research, Creative Peptides can also assemble genes and subcloned them into expression vectors to obtain bioactive peptides.

Every step of peptide synthesis is subject to Creative Peptides' stringent quality control. Typical delivery specifications include:

• HPLC chromatogram
• Mass spec analysis
• Synthesis report
• Certificate of Analyses

Reference

1. Andersson, L., Blomberg, L., Flegel, M., Lepsa, L., Nilsson, B., & Verlander, M. (2000). Large‐scale synthesis of peptides. Peptide Science, 55(3), 227-250.