Introduction Pergolide mesylate salt , also known as 8-beta-((methylthio)methyl)-D-6-propylergoline methanesulfonate, is a dopamine receptor (D receptor) agonist acting like bromocriptine, which is
Introduction Perindopril erbumine is an angiotensioncon vertingenzyme (ACE) inhibitor without sulfhydryl group. It is a chiral drug with good clinical efficacy, high safety and small side effects am
Introduction Secretin is a 27 amino acid polypeptide that is released during acidification in the duodenal cavity and stimulates the secretion of water and bicarbonate by pancreatic ductal cells. T
Introduction Sinapultide (also known as KL4 peptide) is a synthetic protein used to mimic human SP-B. Respiratory distress syndrome (RDS) is characterised by surfactant deficiency leading to higher
Introduction Econazole, commonly used as sulfosalicylate and nitrate salt, is an imidazole broad-spectrum antifungal drug, which can not only interfere with the biosynthesis of fungal cell membrane, b
Introduction PAC-113, as well as a new type of Trp-rich peptide, is a 12 amino-acid fragment of the saliva protein histatin 5 and a histidine-rich antimicrobial peptide with the sequence AKRHHGYKRKFH2
Introduction Secretin belongs to the vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide family and is a basic polypeptide. It consists of amino acids and 27 amino acid resi
Introduction Nafarelin acetate is a gonadotropin-releasing hormone (GnRH) agonist which is as effective as danazol in the treatment of endometriosis. Its mechanism of action is that the desensitizatio
Introduction Obestatin is a 23-amino acid peptide hormone produced in specific epithelial cells of the stomach and small intestine of human. It is present in the gastrointestinal tract, spleen, mammar
Introduction NF-кB activator 1, named Act1, is a 60-kDa (574-aa) polypeptide. Based on its interaction with IKKγ, Act1can be cloned by Leonardi et al. through a yeast-two hybrid screening. Instead of
Introduction Cetrorelix acetate (C70H92ClN17O14, referred to as cetrorelix), a synthetic decapeptide with 5 amino acids in the D-configuration, is a potent, pure competitive antagonist at the human go
Introduction Etomidate, a highly selective intravenous anesthetic agent, was first synthesized at Janssen Pharmaceuticals in the early 1964 and wasused for the induction of general anesthesia and sed
Introduction Vasoconstrictor substances, such as norepinephrine and epinephrine, have been mingled with local anesthetics to decrease their toxic effects and to prolong the depth of the anesthesia in
Introduction Eptifibatide acetate is a white or white-off powder, soluble in water and freely soluble in 1% acetic in water, with the empirical formula C35H49N11O9S2 and molecular weight of 831.96. I
Introduction Topotecan (TPT) is a water-soluble, semi-synthetic camptothecin derivative developed by Smithkline Beecham, USA. Its chemical name is 9-dimethylamino 10-hydroxyhydrocamptothecin, which is
Introduction NG-monomethyl-L-arginine (L-NMMA) acetate, a structural analogue of L-arginine, also named tilarginine acetate and methylarginine acetate, is a non-specific nitric oxide synthase (NOS) in
Introduction DAMME (DA) is a guanine, often referred to as FK 33-824 (FK), which is a long-acting enkephalin analog. Natural enkephalin is metabolized faster in the body and can only exert weak and
Introduction Fertirelin acetate, classified into peptide hormone, is a gonadotropin-releasing hormone (GnRH) antagonist or analogue of luteinizing hormone releasing hormone (LH-RH), which is synthes
Introduction Kassinin, a new peptide of amphibian origin, has been traced in the skin of the African frog Kassina senegalensis. Kassinin belongs to the tachykinin family which are peptides with the sa
Introduction Linaclotide, sold under the brand name Linzess, is a synthetic tetradecapeptide and guanylate cyclase (GC-C) receptor agonist which is a class of compounds that increase the intra- and ex
