Overview of Peptide Purification Process

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Peptide purification refers to the process of isolating and purifying peptides from a mixture. Peptides are short chains of amino acids linked together by peptide bonds. They are synthesized by methods such as solid phase peptide synthesis or recombinant DNA technology. However, these synthesis processes usually result in peptide mixtures containing impurities, by-products, protecting groups and reagents used in the synthesis reaction. Peptide purification is essential to obtain high purity peptides for further characterization, biological research or therapeutic applications. It involves isolating the desired peptide from impurities and obtaining high yield and quality purified peptide samples.

Extraction, purification and isolation procedures of bioactive peptidesFig. 1. Extraction, purification and isolation procedures of bioactive peptides (Journal of Food Science. 2018, 83(1): 6-16).

Approaches to Peptide Purification

Advantages of Peptide Purification

Reference

  1. Admassu H., et al. Bioactive peptides derived from seaweed protein and their health benefits: antihypertensive, antioxidant, and antidiabetic properties. Journal of Food Science. 2018, 83(1): 6-16.
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