Background Aclerastide, one angiotensin receptor agonist, is the active ingredient of DSC127 and its general structure is shown in Fig. 1. Aclerastide is an analog of the naturally occurring peptide,
Introduction Anisomycin, also known by its trade name flagecidin, is a bacterial pyrrolidine antibiotic mostly isolated from Streptomyces griseolus, but it can also be produced from various Streptomyc
Introduction This article will give a brief introduction about atosiban and focus on its role played in the treatment of preterm labor. Atosiban is an oxytocin-receptor antagonists, and it was markete
Introduction Aviptadil acetate, the nonproprietary or generic name for a vasoactive intestinal peptide (VIP), is a synthetic 28-amino-acid VIP (Fig.1). In pulmonary arterial hypertension (PAH), elevat
Introduction Figure 1. Chemical structure of lysipressinLysipressin ([Lys8]-vasopressin) has been identified in the North America opossum (Didelphis virginiana) by amino acid composition and high pres
Introduction Figure 1. Chemical structure of pentagastrinPentagastrin, known as peptavlon, is a synthetic pentapeptide that promotes the secretion of gastric acid, pepsin and internal factors. The fac
Introduction Figure 1. The structural formula of ornipressinOrnipressin is a synthetic analogue of vasopressin, which is replaced by Ornipressin at residue 8 of the cyclic nonapeptide. As an effective
Introduction Figure 1. The structural formula of montirelinMontirelin, an analog of thyrotrophin-releasing hormone (TRH) is more potent and acts longer than TRH, producing beneficial effects in animal
Introduction Dynorphin A (1-13) [Dyn-A (1-13)] is a short-chain polypeptide containing 13 amino acids and having extensive biological activity in vivo. It is an important neurotransmitter in the centr
Introduction Deslorelin acetate, marketed under the trade names Ovuplant, SucroMate and Suprelorin, is an injectable gonadotropin releasing hormone super agonist (GnRH agonist), also known as a LHRH a
Introduction Somatostatin (SST) is a peptide compound synthesized by neuroendocrine cells and other cells that can label tumor cells, but the half-life of SST in the body is extremely short (4 min), w
Introduction Iron chelating agent is a new type of iron-removing treatment based on the combination of directional and in vivo iron ions, effectively improving iron excretion, reducing iron content in
Introduction Studies on the binding affinities of darifenacin hydrobromide and human muscarinic receptor subtypes show strong selectivity for M receptors, a competitive muscarinic M3 receptor antagoni
Introduction Dalbavancin, marketed under the brand name of Dalvance, is a new semi-synthetic glycopeptide antibiotic for antibacterial treatment of complex infections and infections caused by multi-dr
Introduction Corticotropin-releasing factor (CRF) is a 41 amino acid peptide that is an important hormone in the hypothalamic-pituitary-adrenalin axis (HPA axis) and is closely related to stress regul
Introduction Cyclosporin A (CsA) is a cyclic polypeptide consisting of 11 amino acids, which contains a new amino acid containing 9 carbons with an ethylene double bond, and is widely used as a second
Introduction The thymopentin is a small peptide consisting of 5 amino acid residues (Arg-Lys-Asp-Val-Tyr) from thymosin. It has the same biological activity as thymogen, which can regulate the imbalan
Introduction Tetracosactide (also known as Tetracosactide) is a synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of adrenocorticotropic hormone. Adrenocorticotropic H
Introduction Somatostatin is the main hemostatic drug in the clinic, and its derivative octreotide has been confirmed by many studies that it has a significant effect in treating upper gastrointestina
Introduction Teriparatide is a human parathyroid hormone analog with the same structure as the N-terminal 34 amino acid sequence of native parathyroid hormone (PTH). It binds to the PTH-1 receptor and
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ClC-2 chloride channels are voltage-gated ion channels that are expressed in neuronal and epithelial cells wher ...
Gap 19 is a nonapeptide derived from the cytoplasmic loop (CL) of Connexin-43 (Cx43). Cx43 is a predominant card ...
Topotecan (TPT) is a water-soluble, semi-synthetic camptothecin derivative developed by Smithkline Beecham, USA. ...
Abarelix, sold under the brand name Plenaxis, is a synthetic decapeptide and Gonadotropin-releasing hormone (GnR ...
Delcasertib, also known as KAI-9803, is a 23-amino acid peptide and δ-protein kinase C (δ-PKC) inhibitor. KAI-9 ...