R8-T198wt

R8-T198wt is a potent inhibitor used in the biomedical industry for targeted treatment of mutant forms of epidermal growth factor receptor (EGFR) associated with lung adenocarcinoma. It effectively blocks the downstream signaling pathways, impedes tumor growth, and enhances patient outcomes.

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CAT#GR2231
CAS2305815-72-7
Chemical Name(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoic acid
M.F/FormulaC111H211N59O26S
M.W/Mr.2820.33
SequenceGGGRRRRRRRRGCKKPGLRRRQT
Labeling TargetPIM Kinase
AppearanceWhite solid
Purity>95%
ActivityInhibitor
Areas of InterestCancer
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