R 892

Potent and selective bradykinin B1 receptor antagonist (ID50 values are 2.8 and > 600 nM at B1 and B2 receptors respectively), which shows no intrinsic agonist activity and is resistant to aminopeptidase and kininase II (ACE) cleavage. Displays hypertensive activity in vivo.

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CAT#R1002
CAS229030-05-1
M.F/FormulaC58H83N13O12
M.W/Mr.1154.37
SequenceAc-Lys-Arg-Pro-Pro-Gly-aMePhe-Ser-D-2Nal-Ile-OH
Labeling TargetBradykinin B1 receptor
AppearanceWhite lyophilised solid
Purity>98%
ActivityAntagonist
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