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LCKLSL

LCKLSL is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL also inhibits the generation of plasmin and has anti-angiogenic roles.

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CAT#	R1923
Chemical Structure
CAS	533902-29-3
M.F/Formula	C30H57N7O8S
M.W/Mr.	675.88
Sequence	One Letter Code: LCKLSL Three Letter Code: Leu-Cys-Lys-Leu-Ser-Leu
Application	Cardiovascular Disease
Activity	Inhibitor

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Storage	Store at -20°C
Solubility	Soluble in DMSO
Shipping Condition	Room temperature in continental US; may vary elsewhere.
References	1. Mallika Valapala, et al. A Competitive Hexapeptide Inhibitor of Annexin A2 Prevents Hypoxia-Induced Angiogenic Events. J Cell Sci. 2011 May 1;124(Pt 9):1453-64.