Gonadorelin
Gonadorelin is a trophic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released from GnRH neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hypothalamic–pituitary–gonadal axis.
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| CAT# | 10-101-166 |
| CAS | 33515-09-2(net) |
| Synonyms/Alias | GONADORELIN(2MG);Gonaderelin acetate;GONADORELIN ACETATE;Gonadorelin Acetate/GnRH;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2-amino-2-oxoethyl)amino]-oxomethyl]-1-pyrrolidinyl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methy |
| M.F/Formula | C55H75N17O13.C2H4O2 |
| M.W/Mr. | 1242.36 |
| Sequence | Three Letter Code: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 acetate salt |
| Application | Gonadorelin is also known as LHRH. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis. |
| Appearance | Solid powder |
| Activity | Agonist |
| Biological Activity | Gonadorelin is a synthetic decapeptide with a structure identical with the natural Gonadotrophin. Releasing Hormone (Gn-RH) in mammalian species. |
| Target | Gonadotropin-releasing hormone receptor |
| Length | 10 |
Storage | Desiccate at -20°C |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
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