Parstatin (human)

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CAT#GR2141
CAS1065755-99-8
Synonyms/AliasCell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.
M.F/FormulaC191H330N64O53S3
M.W/Mr.4467.29
SequenceMGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPR
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