Marizomib

Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity. Marizomib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Malignant Glioma, among others.

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CAT No:MFP-014

CAS No:437742-34-2

Synonyms/Alias:salinosporamide A; (-)-Salinosporamide A; UNII-703P9YDP7F

Chemical Name:(1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

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M.F/FormulaC15H20ClNO4
M.W/Mr.313.77
InChIInChI=1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)/t9-,10+,11+,14+,15+/m1/s1
InChI KeyNGWSFRIPKNWYAO-SHTIJGAHSA-N
Canonical SMILESCC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl
Isomeric SMILESC[C@]12[C@H](C(=O)N[C@]1(C(=O)O2)[C@H]([C@H]3CCCC=C3)O)CCCl
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