delta PKC (8-17); PKC d Inhibitor
delta PKC (8-17); PKC d Inhibitor
This peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice.
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| CAT# | X21142 |
| M.W/Mr. | 1116.2 |
| Sequence | One Letter Code: SFNSYELGSL
Three Letter Code: H-Ser-Phe-Asn-Ser-Tyr-Glu-Leu-Gly-Ser-Leu-OH |
| Storage | -20°C |
References | 1. Bright, R. et al. J Neurosci 24, 6880 (2004).
2. Tanaka, M. et al. Circulation 110, 194 (2004).
3. Braun, M and D. Mochly-Rosen. J Mol Cell Cardiol 35 895 (2003).
4. Chen, L. et al. Proc Natl Acad Sci USA 98, 11114 (2001). |
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