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An unusual amino acid used in Solid Phase Peptide Synthesis (SPPS) as: A) a precursor to the tritium-induced Norvaline peptides,1 B) in the synthesis of branched peptides using a palladium-catalyzed coupling reaction,2 and C) as a reagent in the dual-catalyst Sonogashira coupling reaction.3
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M.F/Formula | C10H15NO4 |
M.W/Mr. | 213.2•181.3 |
References | 1. Vallee, M. R. J.; Majkut, P.; Wilkening, C. W.; Muller, G.; Hackenberger, C. P. R. Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins.Org. Lett. 2011 (13) 5440-5443. 2. Staudinger, H.; Meyer, J. UberneueorganischePhosphorverbindungen III. Phosphinmethylenederivative und Phosphinimine. Helvetica Chim. Acta. 1919 (2) 635-646. |
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