Thymopentin

Thymopentin is a synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties. Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle.

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CAT#	T07011
CAS	177966-81-3
Synonyms/Alias	TP-5; Arg-Lys-Asp-Val-Tyr; ORF-15244; Thymopoietin-5, Thymopoietin (32-36) (human, mouse), Thymopoietin I/II (32-36) (bovine), TP-5, (Asp34)-Thymopoietin III (32-36) (bovine); L-arginyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosine
Chemical Name	(3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
M.F/Formula	C30H49N9O9
M.W/Mr.	679.8
Sequence	One Letter Code: RKDVY Three Letter Code: H-Arg-Lys-Asp-Val-Tyr-OH
Activity	Inhibitor
Areas of Interest	AIDS
Target	Mycobacteria phagocytosis

CAT#	Product Name	Inquiry
10-101-244	[Tyr0]-C-Type Natriuretic Peptide (32-53)	Inquiry
HB00116	AOD9604	Inquiry
10-101-21	Histrelin Acetate	Inquiry
10-101-67	Afamelanotide acetate	Inquiry
10-101-267	Arg-Gly-Asp	Inquiry

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Length	3
Storage	Desiccate at -20°C
Solubility	DMF: 30 mg/ml DMSO: 25 mg/ml Ethanol: 1 mg/ml PBS (pH 7.2): 10 mg/ml
Shipping Condition	Room Temperature in continental US; may vary elsewhere
InChI	InChI=1S/C30H49N9O9/c1-16(2)24(28(46)38-22(29(47)48)14-17-8-10-18(40)11-9-17)39-27(45)21(15-23(41)42)37-26(44)20(7-3-4-12-31)36-25(43)19(32)6-5-13-35-30(33)34/h8-11,16,19-22,24,40H,3-7,12-15,31-32H2,1-2H3,(H,36,43)(H,37,44)(H,38,46)(H,39,45)(H,41,42)(H,47,48)(H4,33,34,35)/t19-,20-,21-,22-,24-/m0/s1
InChI Key	PSWFFKRAVBDQEG-YGQNSOCVSA-N
Canonical SMILES	CC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)N
Isomeric SMILES	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)N