Thailanstatin A

Thailanstatin A is a splicesosome inhibitor that acts via suppressing RNA-polymerase II. It is effective against cancers, and can be used as a payload for ADCs.

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CAT#MFP-002
Chemical Structure
CAS1426953-21-0
Synonyms/AliasTST-A; 1,6-Dioxaspiro[2.5]octane-5-acetic acid, 7-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(2Z,4S)-4-(acetyloxy)-1-oxo-2-penten-1-yl]amino]tetrahydro-3,6-dimethyl-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl]-8-hydroxy-, (3R,5S,7R,8R)- Thailandstatin A Thailanstatin A
M.F/FormulaC28H41NO9
M.W/Mr.535.63
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