Sincalide Ammonium Salt

Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract.

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CAT#	10-101-31
CAS	25126-32-3 (net)
Background	Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract. >> Read More
Synonyms/Alias	CCK-8; Cholecystokinin Octapeptide; (Des-Pyr1,Des-Gln2,Met5)-Caerulein
M.F/Formula	C49H62N10O16S3
M.W/Mr.	1143.3
Sequence	Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
Labeling Target	Gastrin/cholecystokinin receptor
Application	Sincalide ammonium salt is used for the diagnosis of bile tract and pancreatic diseases, and for the clinical radiology of the intestinal tract.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Biological Activity	Sincalide ammonium (Cholecystokinin octapeptide ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is an agent that promotes gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders.
Areas of Interest	Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-01	Tetracosactide Acetate	2933.5	C136H210N40O31S	Inquiry
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Source#	Synthetic
Solubility	Soluble in DMSO
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Long-term Storage Conditions	-20 °C
BoilingPoint	N/A
ShelfLife	>2 years if stored properly
References	To establish normal gallbladder ejection fraction (GBEF) values for two sincalide (cholecystokinin [CCK]) infusion dose rates, 0.01 microg per kilogram of body weight infused for 3 minutes and 0.01 microg/kg infused for 60 minutes. Ziessman, H. A., Muenz, L. R., Agarwal, A. K., & ZaZa, A. A. (2001). Normal values for sincalide cholescintigraphy: comparison of two methods. Radiology, 221(2), 404-410.
Melting Point	N/A