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Sar-[D-Phe8]-des-Arg9-Bradykinin

Sar-[D-Phe8]-des-Arg9-Bradykinin is a modified bradykinin analog incorporating N-terminal sarcosine and a D-aromatic substitution that alters conformational rigidity. These modifications influence binding orientation and folding behavior. The sequence supports structure–function correlation studies. Researchers employ it in mechanistic analyses of bradykinin derivatives.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1099

CAS No:126959-88-4

Synonyms/Alias:126959-88-4;Sar-[D-Phe8]-des-Arg9-Bradykinin;[Sar,D-Phe8,des-Arg9]bradykinin;Bradykinin, sar-(D-phe(8))des-arg(9);1-8-Bradykinin, N2-(N-methylglycyl)-8-D-phenylalanine-;(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid;Spa-BK;Sar[DPhe8][des-Arg9]BK;R-838 compound;Sar-(D-phe(8))des-arg(9)-BK;[sarcosine,D-Phe8,des-Arg9]bradykinin;[N-methylglycine,D-Phe8,des-Arg9]bradykinin;Sar[Dphe...8...][des-Arg...9...]Bradykinin;GTPL643;H-(Sar)RPPGFSP(dF)-OH;SCHEMBL20298701;BFA95988;AKOS024457495;Sar- [D-Phe8] -des-Arg9-Bradykinin;DA-57655;HY-103291;CS-0027207;Q27088695;Bradykinin, N2-(N-methylglycyl)-8-D-phenylalanine-9-de-L-arginine-;(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[(2-methylaminoacetyl)amino]pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid;

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M.F/Formula
C47H66N12O11
M.W/Mr.
975.1
Sequence
One Letter Code:GRPPGFSPF
Three Letter Code:H-Sar-Arg-Pro-Pro-Gly-Phe-Ser-Pro-D-Phe-OH
InChI
InChI=1S/C47H66N12O11/c1-50-26-38(61)53-31(16-8-20-51-47(48)49)43(66)59-23-11-19-37(59)45(68)58-22-9-17-35(58)41(64)52-27-39(62)54-32(24-29-12-4-2-5-13-29)40(63)56-34(28-60)44(67)57-21-10-18-36(57)42(65)55-33(46(69)70)25-30-14-6-3-7-15-30/h2-7,12-15,31-37,50,60H,8-11,16-28H2,1H3,(H,52,64)(H,53,61)(H,54,62)(H,55,65)(H,56,63)(H,69,70)(H4,48,49,51)/t31-,32-,33+,34-,35-,36-,37-/m0/s1
InChI Key
YIUBSFCQATYQJB-VCMDLEIESA-N

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