Risuteganib

Risuteganib, also known as ALG1001, is an anti-integrin that downregulates oxidative stress and restores homeostasis, and targets three integrin receptors that are implicated in dry age-related macular degeneration (AMD) in order to restore homeostasis in the retina.

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CAT#	R1894
Chemical Structure
CAS	1307293-62-4
Synonyms/Alias	ALG 1001; ALG1001; ALG-1001;H-Gly-Arg-Gly-Cys(O3H)-Thr-Pro-OH;Gly-Arg-Gly-Cys(acid)-Thr-Pro
Chemical Name	(2S)-1-[(2S,3R)-2-[[(2R)-2-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-sulfopropanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid; glycyl-L-arginyl-glycyl-L-cysteyl-L-threonyl-L-proline
M.F/Formula	C22H39N9O11S
M.W/Mr.	637.666
Sequence	One Letter Code: GRGXTP Three Letter Code: Gly-Arg-Gly-Cys(acid)-Thr-Pro
Appearance	Solid powder

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Size	6
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility	Soluble in DMSO
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
InChI	InChI=1S/C22H39N9O11S/c1-11(32)17(20(37)31-7-3-5-14(31)21(38)39)30-19(36)13(10-43(40,41)42)29-16(34)9-27-18(35)12(28-15(33)8-23)4-2-6-26-22(24)25/h11-14,17,32H,2-10,23H2,1H3,(H,27,35)(H,28,33)(H,29,34)(H,30,36)(H,38,39)(H4,24,25,26)(H,40,41,42)/t11-,12+,13+,14+,17+/m1/s1
InChI Key	MYZAXBZLEILEBR-RVFOSREFSA-N
Canonical SMILES	CC(C(C(=O)N1CCCC1C(=O)O)NC(=O)C(CS(=O)(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)NC(=O)CN)O