Rapamycin

Rapamycin is a macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production.

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CAT#Z10-101-156
CAS53123-88-9
Synonyms/AliasSirolimus; Rapamune; 53123-88-9; AY 22 989; I 2190A
M.F/FormulaC51H79NO13
M.W/Mr.914.18
Labeling TargetSerine/threonine-protein kinase mTOR
ApplicationRapamycin is a potent immunosuppressant, and have both antifungal and antineoplastic properties.
AppearanceWhite to off-white solid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityInhibitor
Biological ActivityRapamycin, a specific inhibitor of mTOR, has been shown to be useful in the treatment of certain diseases.
Areas of InterestImmunosuppressant; Lymphangioleiomyomatosis (LAM)
FunctionsTfiiic-class transcription factor binding
TargetmTOR
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