Q-VD-OPH
Q-VD-OPH is a broad-spectrum caspase inhibitor that blocks caspases-3, -7, -8, -9, -10, and -12. It more effectively inhibits apoptosis and is much less cytotoxic than Z-VAD-FMK and Boc-D-FMK.
Online Inquiry
| CAT# | R0812 |
| CAS | 1135695-98-5 |
| Synonyms/Alias | pan-Caspase inhibitor (fluoromethylketone); N-(2-Quinolyl)-L-valyl-L-aspartyl-(2,6-difluorophenoxy) methylketone |
| M.F/Formula | C26H25F2N3O6 |
| M.W/Mr. | 513.8 |
| Application | Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM). |
| Appearance | White to off-white solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Activity | Inhibitor |
| Solubility | Soluble in DMSO |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
InChI | InChI=1S/C26H25F2N3O6/c1-14(2)23(31-25(35)19-11-10-15-6-3-4-9-18(15)29-19)26(36)30-20(12-22(33)34)21(32)13-37-24-16(27)7-5-8-17(24)28/h3-11,14,20,23H,12-13H2,1-2H3,(H,30,36)(H,31,35)(H,33,34)/t20-,23-/m0/s1 |
InChI Key | OOBJCYKITXPCNS-REWPJTCUSA-N |
Isomeric SMILES | CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2 |
Write a review
Ask a question
My Review for Q-VD-OPH
Required fields are marked with *
×
Ask a Question for Q-VD-OPH
Required fields are marked with *
×
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
