N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt
N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin. Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity.
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| CAT# | R1907 |
| Chemical Structure |  |
| CAS | 88793-79-7 |
| Synonyms/Alias | N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt; Tos-GPK-pNA; Tos-Gly-Pro-Lys-pNA acetate |
| Chemical Name | N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate |
| M.F/Formula | C26H34N6O7S • C2H4O2 |
| M.W/Mr. | 634.7 |
| Storage | -20°C |
Solubility | Ethanol: 50 mg/ml |
Shipping Condition | Room Temperature in continental US; may vary elsewhere. |
InChI | InChI=1S/C26H34N6O7S.C2H4O2/c1-18-7-13-21(14-8-18)40(38,39)28-17-24(33)31-16-4-6-23(31)26(35)30-22(5-2-3-15-27)25(34)29-19-9-11-20(12-10-19)32(36)37;1-2(3)4/h7-14,22-23,28H,2-6,15-17,27H2,1H3,(H,29,34)(H,30,35);1H3,(H,3,4)/t22-,23-;/m0./s1 |
InChI Key | KPGSNEYSJPIZCW-SJEIDVEUSA-N |
Canonical SMILES | CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCCC2C(=O)NC(CCCCN)C(=O)NC3=CC=C(C=C3)[N+](=O)[O-].CC(=O)O |
Isomeric SMILES | CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)NC3=CC=C(C=C3)[N+](=O)[O-].CC(=O)O |
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