MSG 606

Potent human MC1 receptor antagonist (IC50 = 17 nM), and alsoMC3 and MC5 partial agonist (EC50 values are 59 and 1300 nM, respectively). Exhibits binding affinity for A375 melanoma.

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CAT#R1043
CAS1416983-77-1
M.F/FormulaC62H82N20O13S
M.W/Mr.1347.51
SequenceXGHFRWCDRFG(Modifications: X = Butanoic acid, Gly-11 = C-terminal amide, Phe-4 = D-Phe, Trp-6 = D-Trp, carba sulfide bridge between X-1 - Cys-7)
Labeling TargetMC1 receptor
ActivityAntagonist
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