Lysipressin

Lysipressin is a pressor peptide isolated from marsupials and pigs that binds to VP receptors, which are analogous to human Vasopressin 2 (V2) receptors. Lysipressin induces contractions in smooth muscle and potentiates effects of gastric lesioning in animal models.

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CAT#	10-101-23
Chemical Structure
CAS	50-57-7
Background	Lysipressin is a pressor peptide found in marsupials and pigs that binds to VP receptors, which are analogous to human Vasopressin 2 (V2) receptors. Lysipressin induces contractions in smooth muscle and potentiates effects of gastric lesioning in animal models. >> Read More
Synonyms/Alias	lysine vasopressin; LVP; Lysipressin; Lysopressin; Syntopressin; Vasophysin; Pitressin; Postacton; Diapid; Lysylvasopressin; Lysine vasopressin; Lysine pitressin
M.F/Formula	C46H65N13O12S2
M.W/Mr.	1056.2
Sequence	Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt
Labeling Target	Vasopressin receptor
Application	Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels, It is used to treat bleeding esophageal varices.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Biological Activity	Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families. Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase.
Areas of Interest	Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-24	Nafarelin Acetate	1322.5	C10H18N2O7	Inquiry
10-101-64	Montirelin	408.48	C17H24N6O4S	Inquiry
10-101-65	Obestatin (human)	2546.87	C116H176N32O33	Inquiry
10-101-96	Peptide YY (3-36) (human) Acetate	4049.52	C180H279N53O54	Inquiry
10-101-97	Peptide YY (human) Acetate	4309.81	C194H295N55O57	Inquiry

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Source#	Synthetic
Solubility	Soluble in DMSO
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Long-term Storage Conditions	-20 °C
BoilingPoint	1610.4±65.0 °C at 760 mmHg
ShelfLife	>2 years if stored properly
References	The neurohypophyseal hormones of the hippopotamus (Hippopotamus amphibius) and collared peccary (Tayassu angulatus) were isolated by molecular sieving and preparative high-pressure liquid chromatography (HPLC). Oxytocin and arginine vasopressin have been identified by their amino acid compositions and their retention times in HPLC. Lysipressin (lysine vasopressin) was not detected in posterior pituitaries of two hippopotami and nine peccaries (less than 2% of arginine vasopressin in molar ratios). Among the suborder Suiformes of Artiodactyla, the families Hippopotamidae and Tayassuidae do not seem to possess lysipressin, in contrast to the family Suidae in which the pig has lysipressin in place of arginine vasopressin. Rouille, Y., Chauvet, M. T., Chauvet, J., Acher, R., & Hadley, M. E. (1988). The distribution of lysine vasopressin (lysipressin) in placental mammals: a reinvestigation of the Hippopotamidae (Hippopotamus amphibius) and Tayassuidae (Tayassu angulatus) families. General and comparative endocrinology, 71(3), 475-483.
Melting Point	N/A