Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH is a statine-containing peptide analog designed to mimic transition states in protease-catalyzed reactions. Its isovaleryl cap and non-natural residues enhance hydrophobic contacts and metabolic stability. Researchers employ it to probe active-site topology and binding energetics. The peptide aids development of peptidomimetic inhibitors and mechanistic enzymology studies.
1. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry
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