A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor.
CAT# | R1950 |
Chemical Structure | |
CAS | 141732-76-5 |
Synonyms/Alias | Exendin-4 Acetate |
M.F/Formula | C184H282N50O60S•C2H4O2 |
M.W/Mr. | 4246.62 |
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