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Dynamin inhibitory peptide

Dynamin Inhibitory Peptide is a peptide inhibitor of the GTPase dynamin, which competitively blocks binding of dynamin to amphiphysin, thus it prevents endocytosis when administered intracellularly. It lead to GABAA receptor internalization reduce and miniature ISPC amplitude and frequency in neurons expressing GABAA receptors increase.

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CAT#	R0850
CAS	251634-21-6
M.F/Formula	C47H80N18O14
M.W/Mr.	1121.26
Sequence	QVPSRPNRAP
Labeling Target	GTPase dynamin
Purity	>98 %
Activity	Inhibitor

CAT#	Product Name	Inquiry
R1150	Ac-MBP 1-11	Inquiry
R1699	Syntide 2	Inquiry
R1913	Boc-Phe-Leu-Phe-Leu-Phe	Inquiry
R1745	Urotensin II, mouse	Inquiry
R1896	MC-Gly-Gly-Phe-Gly	Inquiry

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Storage	-20°C
Solubility	Soluble in DMSO
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C47H80N18O14/c1-23(2)35(62-36(69)25(48)14-15-33(49)67)44(77)64-19-7-12-31(64)41(74)61-29(22-66)39(72)59-27(10-5-17-56-47(53)54)43(76)63-18-6-11-30(63)40(73)60-28(21-34(50)68)38(71)58-26(9-4-16-55-46(51)52)37(70)57-24(3)42(75)65-20-8-13-32(65)45(78)79/h23-32,35,66H,4-22,48H2,1-3H3,(H2,49,67)(H2,50,68)(H,57,70)(H,58,71)(H,59,72)(H,60,73)(H,61,74)(H,62,69)(H,78,79)(H4,51,52,55)(H4,53,54,56)/t24-,25-,26-,27-,28-,29-,30-,31-,32-,35-/m0/s1
InChI Key	LHQOQXYEPUSHJL-LNIRUYPRSA-N
Isomeric SMILES	C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)N)N
BoilingPoint	N/A
Melting Point	N/A