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Dynamin inhibitory peptide

Dynamin Inhibitory Peptide is a peptide inhibitor of the GTPase dynamin, which competitively blocks binding of dynamin to amphiphysin, thus it prevents endocytosis when administered intracellularly. It lead to GABAA receptor internalization reduce and miniature ISPC amplitude and frequency in neurons expressing GABAA receptors increase.

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CAT#	R0850
CAS	251634-21-6
M.F/Formula	C47H80N18O14
M.W/Mr.	1121.26
Sequence	QVPSRPNRAP
Labeling Target	GTPase dynamin
Purity	>98 %
Activity	Inhibitor

CAT#	Product Name	Inquiry
HB00022	Fitc-FF-FMK	Inquiry
R1927	STh	Inquiry
R1963	Desmopressin Diacetate	Inquiry
R1918	DPDPE	Inquiry
R1468	Kinetensin	Inquiry

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Storage	-20°C
Solubility	Soluble in DMSO
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C47H80N18O14/c1-23(2)35(62-36(69)25(48)14-15-33(49)67)44(77)64-19-7-12-31(64)41(74)61-29(22-66)39(72)59-27(10-5-17-56-47(53)54)43(76)63-18-6-11-30(63)40(73)60-28(21-34(50)68)38(71)58-26(9-4-16-55-46(51)52)37(70)57-24(3)42(75)65-20-8-13-32(65)45(78)79/h23-32,35,66H,4-22,48H2,1-3H3,(H2,49,67)(H2,50,68)(H,57,70)(H,58,71)(H,59,72)(H,60,73)(H,61,74)(H,62,69)(H,78,79)(H4,51,52,55)(H4,53,54,56)/t24-,25-,26-,27-,28-,29-,30-,31-,32-,35-/m0/s1
InChI Key	LHQOQXYEPUSHJL-LNIRUYPRSA-N
Isomeric SMILES	C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)N)N
BoilingPoint	N/A
Melting Point	N/A