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Cilengitide

Specification Technical Data Related Products Customer reviews and Q&A Useful Tools Publications

CAT#	C5501
Chemical Structure
CAS	188968-51-6
Synonyms/Alias	Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
M.F/Formula	C27H40N8O7
M.W/Mr.	588.66
Sequence	One Letter Code: RGDFV
Biological Activity	Potent and selective inhibitor of integrins αvβ3 and αvβ5 (IC50 values are 4.1 and 70 nM, respectively). Exhibits ~10-fold selectivity over gpIIb/IIIa. Increases endothelial monolayer permeability. Also exhibits antiangiogenic activity.

CAT#	Product Name	Inquiry
R04030	Cyclo(-Arg-Gly-Asp-D-Phe-Val)	Inquiry
R04019	RGD-targeted Proapoptotic Peptide	Inquiry
CR00006	RGD-4C	Inquiry
CR00005	E[c(RGDfK)]c(RGDfK)	Inquiry
R04028	Cyclo(-Arg-Gly-Asp-D-Phe-Cys)	Inquiry

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Storage	Desiccate at -20°C
Solubility	Soluble to 10 mg/ml in water
Shipping Condition	Room temperature in continental US; may vary elsewhere.