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CHRG01 is derived from human β-defensin 3 (hBD3) C-terminal amino acids 54 to 67, with all Cys residues substituted with Ser. This substitution removes all disulfide bond linkages within the sequence. CHRG01, like hBD3, displays electrostatic-dependent antimicrobial properties.
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M.W/Mr. | 1662 |
Sequence | One Letter Code: KSSTRGRKSSRRKK Three Letter Code: H-Lys-Ser-Ser-Thr-Arg-Gly-Arg-Lys-Ser-Ser-Arg-Arg-Lys-Lys-OH |
References | Hoover, D. et al. Antimicrob Agents Chemother 47, 2804 (2003). |
1. Implications of ligand-receptor binding kinetics on GLP-1R signalling
4. The spatiotemporal control of signalling and trafficking of the GLP-1R
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