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Substance P (5-11)

Substance P (5-11) captures the C-terminal core responsible for many tachykinin-family receptor interactions. Hydrophobic and basic residues are arranged to stabilize extended conformations. Folding studies highlight its dominant role in binding and signaling. The peptide is widely used in receptor-activation assays and structure–activity investigations.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: S09074

CAS No:51165-09-4

Synonyms/Alias:Substance P (5-11);51165-09-4;Spcthp;Substance P C-terminal heptapeptide;1-Dearginyl-2,4-deprolyl-3-delysine-substance P;CHEMBL311405;(2S)-2-amino-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide;1-Des-arg-2,4-des-pro-3-des-lys-substance P;Substance P, dearginyl(1)-deprolyl(2,4)-delysine(3)-;Substance P (5-11) trifluoroacetate salt;Substance P, 1-de-L-arginine-2-de-L-proline-3-de-L-lysine-4-de-L-proline-;Substance P(5-11);SCHEMBL11309707;DTXSID30965436;HY-P3890;BDBM50283252;DA-58139;FS109598;CS-0626891;substance P,dearginyl(1)-deprolyl(2,4)-delysine(3)-;H-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2; H-QQFFGLM-NH2;(S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carbamoyl-butyrylamino)-4-carbamoyl-butyrylamino]-3-phenyl-propionylamino}-3-phenyl-propionylamino)-acetylamino]-4-methyl-pentanoic acid ((S)-1-carbamoyl-3-methylsulfanyl-propyl)-amide;20-Amino-11,14-dibenzyl-4,7,10,13,16,19-hexahydroxy-17-(3-hydroxy-3-iminopropyl)-5-(2-methylpropyl)-2-[2-(methylsulfanyl)ethyl]-3,6,9,12,15,18-hexaazatricosa-3,6,9,12,15,18-hexaene-1,23-diimidic acid;

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M.F/Formula
C41H60N10O9S
M.W/Mr.
869
Sequence
One Letter Code:QQFFGLM
Three Letter Code:H-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
InChI
InChI=1S/C41H60N10O9S/c1-24(2)20-30(40(59)48-28(36(45)55)18-19-61-3)47-35(54)23-46-38(57)31(21-25-10-6-4-7-11-25)50-41(60)32(22-26-12-8-5-9-13-26)51-39(58)29(15-17-34(44)53)49-37(56)27(42)14-16-33(43)52/h4-13,24,27-32H,14-23,42H2,1-3H3,(H2,43,52)(H2,44,53)(H2,45,55)(H,46,57)(H,47,54)(H,48,59)(H,49,56)(H,50,60)(H,51,58)/t27-,28-,29-,30-,31-,32-/m0/s1
InChI Key
FHHJIELOJQJHCG-JNRWAQIZSA-N

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