Selepressin

Selepressin (INN), also known as [Phe(2),Ile(3), Hgn(4),Orn(iPr)(8)]vasopressin) is a potent, highly selective, short-acting peptide full agonist of the vasopressin 1A receptor and analog of vasopressin which is under development by Ferring Pharmaceuticals for the treatment of vasodilatory hypotension in septic shock.

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CAT#10-101-173
CAS876296-47-8
Synonyms/Alias(Phe2;Ile3;Hgn4;Orn(iPr)8)vasopressin;2-Phe-3-Ile-4-Hgn-8-Orn(iPr)-vasopressin; FE 202158;vasopressin; Phe(2)-Ile(3)-Hgn(4)-Orn(iPr)(8)-;vasopressin; phenylalanyl(2)-isoleucyl(3)-Hgn(4)-ornithyl(isopropyl)(8)-
M.F/FormulaC46H73N13O11S2
M.W/Mr.1048.28232
SequenceH-Cys(1)-Phe-Ile-Nva(CONH2)-Asn-Cys(1)-Pro-Orn(iPr)-Gly-NH2
Labeling TargetArginine Vasopressin Receptor 1A
ApplicationSelepressin is deveolped for the treatment of vasodilatory hypotension in septic shock.
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityAgonist
Biological ActivitySelepressin, also known as FE-202158, is a potent, selective vasopressin V1a receptor agonist potentially for the treatment of septic shock.
Areas of InterestSeptic shock
FunctionsType 1 angiotensin receptor binding
TargetVasopressin Receptor
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