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Polistes Mastoparan

Polistes Mastoparan is a wasp venom peptide adopting an amphipathic α-helix that interacts strongly with membranes and G proteins. Its cationic, hydrophobic balance supports pore formation and signal-modulating actions. Researchers employ it to examine membrane curvature, vesicle fusion, and GTPase activation. The peptide aids biophysical exploration of mastoparan-family mechanisms.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: M02001

Synonyms/Alias:Polistes mastoparan;74129-19-4;Mast cell degranulating peptide (polistes jadwagae);Mastoparan Polistes;SCHEMBL16197250;HY-P2576;VAL-ASP-TRP-LYS-LYS-ILE-GLY-GLN-HIS-ILE-LEU-SER-VAL-LEU-NH2;DA-75327;FP110433;CS-0135818;H-Val-Asp-Trp-Lys-Lys-Ile-Gly-Gln-His-Ile-Leu-Ser-Val-Leu-NH2; H-VDWKKIGQHILSVL-NH2;L-Leucinamide,L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-;

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M.F/Formula
C77H127N21O18
M.W/Mr.
1635
Sequence
One Letter Code:VDWKKIGQHILSVL
Three Letter Code:H-Val-Asp-Trp-Lys-Lys-Ile-Gly-Gln-His-Ile-Leu-Ser-Val-Leu-NH2
Length
14
InChI
InChI=1S/C77H127N21O18/c1-13-43(11)63(97-68(107)50(24-18-20-28-79)88-66(105)49(23-17-19-27-78)89-70(109)54(31-45-34-84-48-22-16-15-21-47(45)48)91-71(110)56(33-60(102)103)93-74(113)61(81)41(7)8)75(114)85-36-59(101)87-51(25-26-58(80)100)67(106)92-55(32-46-35-83-38-86-46)72(111)98-64(44(12)14-2)77(116)94-53(30-40(5)6)69(108)95-57(37-99)73(112)96-62(42(9)10)76(115)90-52(65(82)104)29-39(3)4/h15-16,21-22,34-35,38-44,49-57,61-64,84,99H,13-14,17-20,23-33,36-37,78-79,81H2,1-12H3,(H2,80,100)(H2,82,104)(H,83,86)(H,85,114)(H,87,101)(H,88,105)(H,89,109)(H,90,115)(H,91,110)(H,92,106)(H,93,113)(H,94,116)(H,95,108)(H,96,112)(H,97,107)(H,98,111)(H,102,103)/t43-,44-,49-,50-,51-,52-,53-,54-,55-,56-,57-,61-,62-,63-,64-/m0/s1
InChI Key
XKUYSBUJKLFGFG-XVGFDQGISA-N

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