Plitidepsin

Aplidine is a compound found in tunicates which shows promise in shrinking tumors in pancreatic, stomach, bladder, and prostate cancers. The specific marine organism is Aplidium albicans. Aplidine consists of peptide molecules. In addition to the cancers mentioned above it is also under consideration as a treatment for some types of leukemia.

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CAT#	10-101-177
CAS	137219-37-5
Synonyms/Alias	aplidin;aplidine;plitidepsin;dehydrodidemnin B;
M.F/Formula	C57H87N7O15
M.W/Mr.	1110.33858
Labeling Target	Vascular endothelial growth factor receptor
Application	Intended for the treatment of various forms of cancer.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Activity	Agonist
Areas of Interest	Cancer

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10-101-276	H-His-Tyr-OH	Inquiry
10-101-181	Omiganan	Inquiry
10-101-339	Cu-64 DOTA-TATE	Inquiry
HB00133	Eicosanedioic Acid	Inquiry

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Source#	Synthetic
Storage	-20°C
Solubility	Soluble in DMSO, not soluble in water.
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C57H87N7O15/c1-15-33(8)46-44(66)29-45(67)79-49(32(6)7)48(68)34(9)50(69)58-39(26-30(2)3)54(73)64-25-17-19-41(64)56(75)62(13)43(28-37-20-22-38(77-14)23-21-37)57(76)78-36(11)47(52(71)59-46)60-51(70)42(27-31(4)5)61(12)55(74)40-18-16-24-63(40)53(72)35(10)65/h20-23,30-34,36,39-44,46-47,49,66H,15-19,24-29H2,1-14H3,(H,58,69)(H,59,71)(H,60,70)/t33-,34-,36+,39-,40-,41-,42+,43-,44-,46+,47-,49-/m0/s1
InChI Key	UUSZLLQJYRSZIS-LXNNNBEUSA-N
Isomeric SMILES	CC[C@H](C)[C@@H]1[C@H](CC(=O)O[C@H](C(=O)[C@@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H]3CCCN3C(=O)C(=O)C)C)CC4=CC=C(C=C4)OC)C)CC(C)C)C)C(C)C)O
BoilingPoint	N/A
ShelfLife	>5 years if stored properly
Melting Point	N/A