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Isotope labelled Pasireotide. Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor®, which is used in the treatment of Cushing's disease.
CAT No: 10-101-197
CAS No: 396091-73-9 (non-labelled)
Synonyms/Alias: Cyclo[(2S)-2-phenylglycyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-tyrosyl-L-phenylalanyl-(4R)-4-[[[(2-aminoethyl)amino]carbonyl]oxy]-L-prolyl]-d7; SOM 230-d7SOM 320-d7; Signifor-d7;
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M.F/Formula | C₅₈H₅₉D₇N₁₀O₉ |
M.W/Mr. | 1054.25 |
Sequence | Cyclo[(2S)-2-phenylglycyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-tyrosyl-L-phenylalanyl-(4R)-4-[[[(2-aminoethyl)amino]carbonyl]oxy]-L-prolyl]-d7 |
Labeling Target | Somatostatin receptor |
Application | Pasireotide-d7 is invesgated for the treatment of Cushing's disease, specifically for those patients whom pituitary surgery has not been curative or is not an option. |
Purity | 98.0 % min |
Functions | Somatostatin receptor activity |
Organism | Human |
2. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. TMEM16F and dynamins control expansive plasma membrane reservoirs
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