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Motilin (26-47), human, porcine is an endogenous motilin receptor ligand with Ki and EC50 of 2.3 nM and 0.3 nM in a Chinese hamster ovary cell line.
Peptide Library Construction and Screening
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M.F/Formula | C₁₂₀H₁₈₈N₃₄O₃₅S |
M.W/Mr. | 2699.07 |
Sequence | One Letter Code: FVPIFTYGELQRMQEKERNKGQ three Letter Code: Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Met-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln |
Application | Endogenous motilin receptor ligand (Ki = 2.3 nM) that regulates gastrointestinal motor function. Stimulates contraction of gut smooth muscle (EC50 = 1 nM) and increases pepsin release. |
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