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MCL 0020

MCL 0020 is an effective and selective antagonist of peptidemimetic melanocortin MC4 receptor (IC50 =11.63 nM), exhibits anxiolytic-like activity in vivo.

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CAT#	R0999
CAS	475498-26-1
Synonyms/Alias	N-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide
M.F/Formula	C34H39N7O4
M.W/Mr.	609.73
Sequence	One Letter Code: Ac-2Nal-R-2Nal Three Letter Code: Ac-D-2Nal-Arg-D-2Nal-NH2
Appearance	White lyophilised solid
Purity	>98 %
Activity	Antagonist

CAT#	Product Name	Inquiry
R1989	Trafermin	Inquiry
R1693	Substance P 1-9	Inquiry
R2037	NBI-6024	Inquiry
R1181	Allergen Gal d 4 (46-61), chicken	Inquiry
R1434	HSV-gB2 498-505	Inquiry

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Storage	-20°C
Shipping Condition	Wet ice in continental US; may vary elsewhere
InChI	InChI=1S/C34H39N7O4/c1-21(42)39-30(20-23-13-15-25-8-3-5-10-27(25)18-23)33(45)40-28(11-6-16-38-34(36)37)32(44)41-29(31(35)43)19-22-12-14-24-7-2-4-9-26(24)17-22/h2-5,7-10,12-15,17-18,28-30H,6,11,16,19-20H2,1H3,(H2,35,43)(H,39,42)(H,40,45)(H,41,44)(H4,36,37,38)/t28-,29-,30+/m0/s1
InChI Key	FJFLYSMWSRRMRO-OIFRRMEBSA-N
Isomeric SMILES	CC(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC3=CC4=CC=CC=C4C=C3)C(=O)N