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ICI 154,129

ICI 154129, a peptide analog, is a selective δ opioid antagonist.

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CAT No: R1073

CAS No: 83420-94-4

Synonyms/Alias: N,N-Di(2-propenyl)-L-Tyr-N-[2-[[(S)-2-[[(S)-1-carboxy-3-methylbutyl]amino]-2-oxo-1-benzylethyl]thio]ethyl]-Gly-NH2; M-154129

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M.F/FormulaC34H46N4O6S
M.W/Mr.638.83
SequenceYGFL(Modifications: Tyr-1 = N,N-diallyl-Tyr, Gly-2 - Phe-3 peptide bond replaced with Psi-(CH2S))
Labeling TargetOpioid Receptor
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityAntagonist
Long-term Storage ConditionsSoluble in DMSO
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage ConditionsDry, dark and at 0 - 4 °C
Solubility-20 °C
InChIInChI=1S/C34H46N4O6S/c1-5-17-38(18-6-2)29(21-26-12-14-27(39)15-13-26)32(41)36-23-31(40)35-16-19-45-30(22-25-10-8-7-9-11-25)33(42)37-28(34(43)44)20-24(3)4/h5-15,24,28-30,39H,1-2,16-23H2,3-4H3,(H,35,40)(H,36,41)(H,37,42)(H,43,44)/t28-,29-,30-/m0/s1
InChI KeyCZRZYRKTYLLLRL-DTXPUJKBSA-N
Isomeric SMILESCC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)SCCNC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)N(CC=C)CC=C
BoilingPoint929.4ºC at 760 mmHg
ShelfLife>3 years if stored properly
Melting PointN/A
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