(Glp1)-Apelin-13, human, bovine

[Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist.

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CAT No: HB00085

CAS No: 217082-60-5

Synonyms/Alias: 217082-60-5;[Pyr1]-Apelin-13;(Glp1)-Apelin-13;(pGlu1)apelin-13;Pyr-apelin-13;(Pyr1)apelin-13;[Pyr1]apelin-13;p-Glu-RPRLSHKGPMPF;CHEMBL3184840;CHEBI:138186;(Glp1)-Apelin-13, human, bovine;p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe;[pGlu1]-Apelin-13;L-p-Glu-L-Arg-L-Pro-L-Arg-L-Leu-L-Ser-L-His-L-Lys-Gly-L-Pro-L-Met-L-Pro-L-Phe;5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine;L-Phenylalanine, 5-oxo-L-Prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-;Glu1-apelin-13;[Pyr1]-Apelin 13;(Pyr 1)-Apelin-13;Glp1-Apelin-13 human bovine;BDBM50014619;AKOS024457089;[Pyr1]-Apelin-13 trifluoroacetate salt;NCGC00167298-01;FP109298;G13082;(Glp1)-Apelin-13;Pglu-arg-pro-arg-leu-ser-his-lys-gly-pro-met-pro-phe;

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M.F/Formula	C69H108N22O16S
M.W/Mr.	1533.8
Sequence	One Letter Code:XRPRLSHKGPMPF Three Letter Code:H-Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
Biological Activity	Highly potent pyroglutamyl form of apelin-13. Endogenous ligand for apelin APJ receptor (EC50 = 0.37 nM) that displays potent vascular effects in vivo.

Long-term Storage Conditions	Soluble to 1 mg/ml in water
Shipping Condition	Room temperature in continental US; may vary elsewhere.
InChI	InChI=1S/C69H108N22O16S/c1-39(2)32-47(85-57(96)43(17-9-26-76-68(71)72)82-63(102)52-20-12-29-90(52)65(104)45(18-10-27-77-69(73)74)83-58(97)44-22-23-54(93)80-44)59(98)88-50(37-92)61(100)86-48(34-41-35-75-38-79-41)60(99)81-42(16-7-8-25-70)56(95)78-36-55(94)89-28-11-19-51(89)62(101)84-46(24-31-108-3)66(105)91-30-13-21-53(91)64(103)87-49(67(106)107)33-40-14-5-4-6-15-40/h4-6,14-15,35,38-39,42-53,92H,7-13,16-34,36-37,70H2,1-3H3,(H,75,79)(H,78,95)(H,80,93)(H,81,99)(H,82,102)(H,83,97)(H,84,101)(H,85,96)(H,86,100)(H,87,103)(H,88,98)(H,106,107)(H4,71,72,76)(H4,73,74,77)/t42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-/m0/s1
InChI Key	GGMAXEWLXWJGSF-PEWBXTNBSA-N

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Inquiry
Glucagon

Glucagon (Porcine glucagon) is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon decreases the activity of HNF-4. Glucagon increases HNF4α phosphorylation.

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Somatostatin

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Inquiry
Thymopentin Acetate

Thymopentin, also known as TP-5, is a synthetic derivative of thymopoietin, a thymic hormone, and has immunoregulatory properties. Thymopentin interacts with T cells, reduces endocrine and behavioral responses to experimental stress. It is also found to increase the number of cells undergoing apoptosis in irradiated cells and selectively bind to apoptotic cells.

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(Glp1)-Apelin-13, human, bovine

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