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G-Protein antagonist peptide

Substance P-related peptide which inhibits the binding of G protein to its receptor. Competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.

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CAT#	R0855
CAS	143675-79-0
Synonyms/Alias	GPAnt-2
M.F/Formula	C57H64N12O9S
M.W/Mr.	1093.27
Sequence	Pyr-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2
Appearance	White solid powder
Purity	>98 %
Activity	Inhibitor

CAT#	Product Name	Inquiry
R2032	Glutathionylspermidine	Inquiry
R1774	β-Amyloid 12-20	Inquiry
R0848	Dynamin inhibitory peptide, myristoylated	Inquiry
R2061	Calcitonin gene-related peptide	Inquiry
HB00039	Z-AEVD-FMK	Inquiry

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Storage	-20°C
Solubility	Soluble in DMSO
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C57H64N12O9S/c1-79-24-23-42(51(59)72)64-55(76)46(26-33-29-60-39-16-8-5-13-36(33)39)69-57(78)48(28-35-31-62-41-18-10-7-15-38(35)41)68-54(75)45(25-32-11-3-2-4-12-32)66-56(77)47(27-34-30-61-40-17-9-6-14-37(34)40)67-53(74)44(19-21-49(58)70)65-52(73)43-20-22-50(71)63-43/h2-18,29-31,42-48,60-62H,19-28H2,1H3,(H2,58,70)(H2,59,72)(H,63,71)(H,64,76)(H,65,73)(H,66,77)(H,67,74)(H,68,75)(H,69,78)/t42-,43-,44-,45-,46+,47+,48+/m0/s1
InChI Key	WSYRBHQWMXTCHQ-SFIKJRKMSA-N
Isomeric SMILES	CSCC[C@@H](C(=O)N)NC(=O)[C@@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@@H](CC6=CNC7=CC=CC=C76)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]8CCC(=O)N8
BoilingPoint	N/A
Melting Point	N/A