Beta-Secretase Inhibitor 1

This statine-based substrate analog, ?-secretase inhibitor P10–P4’ statV, is used in the inhibition of ?-secretase activity from homogenized wild-type mouse cortices and from BACE-purified from human brain.

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M.F/Formula1651.9
SequenceOne Letter Code: KTEEISEVN-Sta-VAEF (Sta = statine)
Three Letter Code: H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe-OH
Length16
ReferencesSinha, S. et al. Nature 402, 537 (1999).
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