Agitoxin 2

Agitoxin-2 is an effective and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels, which inhibits Kv1.1 with an IC50 value of around 140 pM and Kv1.3 with an IC50 value of around 200 pM.

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CAT#R0978
CAS168147-41-9
M.F/FormulaC169H278N54O48S8
M.W/Mr.4090.87
SequenceGVPINVSCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPK
(Disulfide bridge: Cys8 and Cys28,Cys14 and Cys33,Cys18 and Cys35)
Labeling TargetKv1.1 and Kv1.3 channels
AppearanceWhite lyophilized solid
Purity>98%
ActivityBlocker
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