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MOTS-c is a mitochondrial-derived peptide described as a bioactive 16 amino acid peptide.
CAT No: 10-101-219
CAS No: 1627580-64-6
Synonyms/Alias: Mots-c;1627580-64-6;UNII-A5CV6JFB78;MOTS-c (human) (trifluoroacetate salt);A5CV6JFB78;Mitochondria-derived peptide mots-c;EX-A6267;HY-P2048;DA-65618;CS-0107608;Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg;L-Arginine, L-methionyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-alpha-glutamyl-L-methionylglycyl-L-tyrosyl-L-isoleucyl-L-phenylalanyl-L-tyrosyl-L-prolyl-L-arginyl-L-lysyl-L-leucyl-;L-Methionyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-alpha-glutamyl-L-methionylglycyl-L-tyrosyl-L-isoleucyl-L-phenylalanyl-L-tyrosyl-L-prolyl-L-arginyl-L-lysyl-L-leucyl-L-arginine;
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M.F/Formula | C101H152N28O22S2 |
M.W/Mr. | 2174.6 |
Sequence | One Letter Code:MRWQEMGYIFYPRKLR Three Letter Code:H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH |
Appearance | White powder |
Biological Activity | promotes biosynthesis of the endogenous amp analog aicar and consequently amp-activated protein kinase (ampk), induces cellular and systemic glucose uptake and improves insulin sensitivity. |
Long-term Storage Conditions | Soluble in water at 0.5mg/ml |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
InChI | InChI=1S/C101H152N28O22S2/c1-7-57(4)83(96(148)126-76(50-58-19-9-8-10-20-58)92(144)127-78(52-60-30-34-63(131)35-31-60)97(149)129-46-18-27-79(129)95(147)122-69(25-16-44-112-100(107)108)86(138)118-67(23-13-14-42-102)87(139)124-74(49-56(2)3)91(143)123-73(98(150)151)26-17-45-113-101(109)110)128-94(146)75(51-59-28-32-62(130)33-29-59)116-81(133)55-115-85(137)72(41-48-153-6)121-90(142)71(37-39-82(134)135)119-89(141)70(36-38-80(104)132)120-93(145)77(53-61-54-114-66-22-12-11-21-64(61)66)125-88(140)68(24-15-43-111-99(105)106)117-84(136)65(103)40-47-152-5/h8-12,19-22,28-35,54,56-57,65,67-79,83,114,130-131H,7,13-18,23-27,36-53,55,102-103H2,1-6H3,(H2,104,132)(H,115,137)(H,116,133)(H,117,136)(H,118,138)(H,119,141)(H,120,145)(H,121,142)(H,122,147)(H,123,143)(H,124,139)(H,125,140)(H,126,148)(H,127,144)(H,128,146)(H,134,135)(H,150,151)(H4,105,106,111)(H4,107,108,112)(H4,109,110,113)/t57-,65-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,83-/m0/s1 |
InChI Key | WYTHCOXVWRKRAH-LOKRTKBUSA-N |
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