KALA

This is a cationic amphipathic cell-penetrating peptide (CPP). It assumes an α-helix conformation when the pH is 7.5. KALA binds oligonucleotides and disrupts cell membrane; therefore, it can be used as a DNA transfection reagent.

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M.F/FormulaC144H248N40O35S
M.W/Mr.3131.8
SequenceH-Trp-Glu-Ala-Lys-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Ala-Lys-His-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Lys-Ala-Cys-Glu-Ala-OH
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