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Gap 26 is a connexin mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
CAT No: R1374
CAS No: 197250-15-0
Synonyms/Alias: Gap 26;197250-15-0;Gap26;GAP 26 trifluoroacetate salt;MFCD06411601;Gap 26 TFA;H-Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg-OH;AKOS024456874;AKOS040758724;DA-53508;FG110169;D80917;Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg;H-Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg-OH; H-VCYDKSFPISHVR-OH;
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M.F/Formula | C70H107N19O19S |
M.W/Mr. | 1550.8 |
Sequence | One Letter Code:VCYDKSFPISHVR Three Letter Code:H-Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg-OH |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
InChI | InChI=1S/C70H107N19O19S/c1-7-38(6)56(67(105)85-50(33-91)61(99)81-46(29-41-31-75-35-77-41)60(98)87-55(37(4)5)66(104)79-44(69(107)108)18-13-25-76-70(73)74)88-64(102)52-19-14-26-89(52)68(106)48(28-39-15-9-8-10-16-39)83-62(100)49(32-90)84-57(95)43(17-11-12-24-71)78-59(97)47(30-53(93)94)82-58(96)45(27-40-20-22-42(92)23-21-40)80-63(101)51(34-109)86-65(103)54(72)36(2)3/h8-10,15-16,20-23,31,35-38,43-52,54-56,90-92,109H,7,11-14,17-19,24-30,32-34,71-72H2,1-6H3,(H,75,77)(H,78,97)(H,79,104)(H,80,101)(H,81,99)(H,82,96)(H,83,100)(H,84,95)(H,85,105)(H,86,103)(H,87,98)(H,88,102)(H,93,94)(H,107,108)(H4,73,74,76)/t38-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,54-,55-,56-/m0/s1 |
InChI Key | FDPIMWZHGJNESB-VCSXYVMHSA-N |
References | Chaytor et al (1997) Peptides homologous to extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in rabbit arteries. J.Physiol. 503 99. Braet et al (2003) Photoliberating inositol-1,4,5-trisphosphate triggers ATP relea |
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