β-Nicotinamide Mononucleotide
β-Nicotinamide Mononucleotide
β-Nicotinamide Mononucleotide (β-NMN) is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate β-NMN, which is subsequently converted to NAD+ by β-NMN adenyltransferase. β-NMN has several beneficial pharmacological activities. Mostly mediated by its involvement in NAD+ biosynthesis, including its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity.
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| CAT# | 10-101-324 |
| CAS | 1094-61-7 |
| Synonyms/Alias | β-NMN, β-Nicotinamide ribose monophosphate, NMN |
| Chemical Name | 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-pyridinium, inner salt |
| M.F/Formula | C11H15N2O8P |
| M.W/Mr. | 334.2 |
| Application | β-Nicotinamide mononucleotide (β-NMN), a key β-NAD+ intermediate, has been shown to enhance β-NAD+ biosynthesis and ameliorate various pathologies in mouse disease models. |
| Appearance | White to off-white powder |
| Purity | ≥ 98% (HPLC) |
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