Nesiritide Acetate is a brain natriuretic peptide secreted by the human heart in response to cardiac volume or pressure.
CAT# | 10-101-262 |
CAS | 114471-18-0 |
Synonyms/Alias | Brain Natriuretic Peptide-32; BNP-32 |
M.F/Formula | C143H244N50O42S4 |
M.W/Mr. | 3464.1 |
Sequence | One Letter Code: SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH Three Letter Code: H-Ser-Pro-Lys-Met-Val-Gin-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-lle-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH (Disulfide Bridge Cys10-Cys26) |
Appearance | White to off white powder |
Purity | ≥98% (HPLC) |
Activity | Agonist |
Biological Activity | Nesiritide acetate is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. |
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