Keratin K18-C
This peptide corresponds to human keratin K18 amino acids 26-38, with an additional C-terminal cysteine. The sequence is identical to mouse K18 except that human K18 Val28 is replaced by alanine in the mouse sequence. Members of the 14-3-3 protein family bind the human intermediate filament protein keratin 18 (K18) in-vivo, in a cell-cycle- and phosphorylation-dependent manner. K18 Ser33 phosphorylation is essential for the association of K18 with 14-3-3 proteins and plays a role in keratin organization and distribution.
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| CAT# | X21198 |
| M.W/Mr. | 1418.5 |
| Sequence | One Letter Code: RPVSSAApSVYAGAC
Three Letter Code: H-Arg-Pro-Val-Ser-Ser-Ala-Ala-pSer-Val-Tyr-Ala-Gly-Ala-Cys-OH |
| Storage | -20°C |
References | Ku, NO. et al. EMBO J. 17, 1892 (1998). |
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