Icatibant Acetate

Icatibant Acetate is the acetate salt form of icatibant, an antagonist of the human bradykinin B2 receptor (B2R).

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CAT#HB00111
CAS138614-30-9
M.F/FormulaC59H89N19O13S.C2H4O2
M.W/Mr.1364.59
ApplicationThree Letter Code: D-Arg-L-Arg-L-Pro-L-Hyp-Gly-L-(2-thienyl)Ala-L-Ser-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3β,7aβ)-octahydro-1H-indole-2-carbonyl-L-Arg
ActivityAntagonist
Biological ActivityIcatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively.
TargetBradykinin Receptor
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