Histone deacetylase, HDAC substrate
Histone deacetylase, HDAC substrate
This novel fluorogenic substrate of HDACs was synthesized with an epsilon-acetylated lysyl moiety and an adjacent MCA moiety at the C-terminus of the peptide chain. The assay utilizing this substrate provides a good tool to characterize the HDAC activity. HDACs are important enzymes for the transcriptional regulation of gene expression.
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| CAT# | H10027 |
| M.W/Mr. | 600.7 |
| Sequence | One Letter Code: Ac-RGK(Ac)-AMC
Three Letter Code: Ac-Arg-Gly-Lys(Ac)-AMC |
| Storage | -20°C |
References | Wegener, D. et al. Chem. Biol. 10, 61 (2003). |
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